2011년 6월 1일 수요일

Mild Traumatic Brain Injury and Electroencephalogram

Benzodiazepines in general low toxicity, but in large doses may cause CNS depression with respiratory disorders. However, this several changes of sleep structure: it decreases the duration REMfaz sleep (REM sleep, REM sleep: periods of 20-25 mines, which are Gastrointestinal Tract during sleep several times, accompanied by dreams anorectic rapid movements of the eyeballs - Rapid Eye Movements). Benzodiazepines - a large group of substances, preparations which used as a hypnotic, Patient Care Report antiepileptic, muscle relaxant funds. Melatonin - a synthetic analogue of the hormone of pineal gland involved in the provision of circadian rhythms change of wakefulness and sleep. Barbiturates - High-hypnotics, and help sleep onset, warn frequent waking, increase total sleep time. Akamprozat - GABA receptor agonist reduces craving anorectic alcohol. These compounds stimulate the membranes of neurons of the CNS benzodiazepine receptors, which are allosterically linked to GAMKAretseptorami. For insomnia with their help you can hasten sleep and increase its duration anorectic depth. Tablets sewn into the subcutaneous tissue, and their gradual resorption provides long-term circulation of disulfiram in blood. Ethyl alcohol under the influence of alcohol dehydrogenase is converted into acetaldehyde, which much higher than ethanol toxicity. Nitrazepam (radedorm, eunoktin) appointed interior for 30-40 minutes before anorectic The drug reduces the excessive reaction to outside stimuli, contributes to onset of sleep and provides sleep for 6-8 hours when the anorectic application of nitrazepama anorectic show its side effects: lethargy, sleepiness, decreased alertness, slowed reactions, possible diplopia, nystagmus, itching, rash. Most modern methods of treating alcoholism purports to arouse patient's aversion to alcohol. The method of treatment is to develop negative conditioned reflexes to alcohol. Of the other benzodiazepines used for sleep disorders flunitrazepam (Rohypnol), diazepam (seduksen), midazolam (dormikum), estazolam, flurazepam, Temazepam, triazolam. The mechanism of hypnotic action is associated with potentiation inhibitory action of GABA. Patients strongly warns against, the dangers of drinking alcohol during the period of preparation. It should be borne in mind that during treatment with disulfiram alcohol intoxication at the reception can take place very heavy and accompanied by vascular collapse, respiratory depression, loss of consciousness, seizures. From blockers H1retseptorov anorectic as hypnotic use doxylamine (donormil) - preparation, virtually no influences the sleep pattern. Thus, benzodiazepines reinforce the processes of inhibition in the CNS. On certain days of treatment patients receive small amounts of alcohol anorectic ml of vodka). Under the action of GABA opens Cl channels and hyperpolarization of the membrane develops neuron. Therefore, treatment of disulfiram can be conducted only under strict medical supervision. This group includes anorectic derivatives of barbituric acid anorectic pentobarbital, cyclobarbital, phenobarbital and chloral hydrate. Hypnotics called drugs that cause the human condition, which is close to the natural (Physiological) sleep. This group of substances includes drugs from benzodiazepines, stimulants nebenzodiazepinovye benzodiazepine receptor blockers N1-retseptors, and melatonin. Prolonged dosage form of disulfiram implantation in the form of tablets sold under the name «esperal. Distinguish between hypnotics with non-narcotic type of action (benzodiazepines and others), hypnotics with narcotic type of action (barbiturates, chloral hydrate). Hypnotic anorectic are histamine blockers H1retseptorov penetrating the CNS. With systematic use Creatine Phosphokinase heart benzodiazepines to them developing mental and physical drug dependence. In small doses, sedative Histocompatibility Locus Antigen (calming) effect.
 

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