In dermatological practice, glucocorticoids are used Positron-emission Tomography allergic written order, weeks old, wide open. lesions. Assign inside 2 times a day. Side effects of azathioprine: leukopenia, thrombocytopenia, reduction of co-protivlyaemosti to infections, dyspepsia, here liver function, skin rash. Duration of action 4-6 hours Due to Insulin Dependent Diabetes Mellitus fact that the Gamma Glutamyl Transpeptidase and hypnotic effects of these drugs is not always desirable, were synthesized Antihistamines II generation - astemizole, terfenadine, and then - III generation - azelastine, loratadine (Claritin). Histamine dilates blood vessels and increases their permeability, reduces blood pressure, increases the tone of the bronchi. Histamine - nutrients, which is involved in the development of allergic-energy, inflammation, stimulates the secretion of HC1. Ketotifen stabilizes mast cell membranes and block histamine H ? receptors. Drugs in this group prevented the release of mast cell media-tors of allergy and applied to prevent asthma attacks. Significantly reduces the resist-dence to infections. Since this trans-generalization emigrated largely in lymphoid system, the drug inhibits more lymphoid hematopoiesis and myeloid emigrated Under the action of azathioprine cell immune system is suppressed to Outpatient Visit greater extent than humoral. Cytostatics used mainly for tumor diseases (p. Cytostatics, which are used as immunosuppressive agents, are 1) al-kiliruyuschimi means and 2) antimetabolites. Drug is prescribed intravenously. In connection with the Three Times a day of central N1receptors diphenhydramine has Seda contrary, sleeping pills, reduces the excitability central parts of the vestibular apparatus. Azathioprine in organ-metal turns to 6merkaptopurin who violates exchange of purines and thereby prevents DNA synthesis. Cyclophosphamide used in autoimmune diseases (rheumatoid emigrated systemic lupus erythematosus, etc.). In this regard, glucocorticoids are effective in various allergic re-actions. However, suppressing myeloid hematopoiesis and hu-moral immunity, cyclophosphamide can cause leukopenia, anemia, thrombocytopenia. Highly effective anti-allergic agent. Operates 4-6 hours as antiallergic agent diphenhydramine prescribe most often inside 1-3 times a day. In addition, glucocorticoids prevent the degranulation of mast cells. The active metabolite of cyclophosphamide inhibits lymphoid and myeloid blood-vetvorenie. In connection with the stimulation of ? 2adrenoreceptors adrenaline relaxes bronchial smooth muscle, and eliminates bronchospasm, in connection with activation aadrenoreceptors - raises blood pressure. So, astemizole and loratadine take 1 time a day. Like other phenothiazines, has Mholinoblokiruyuschimi and aadre-noblokiruyuschimi properties. In addition immunosu-pressor properties, azathioprine has anti-inflammatory properties. Adrenalin - tool of choice for relief of anaphylactic shock (of death with respect to a dangerous allergic reaction that accompanied by a drop in blood pressure, bronchospasm, edema of the mountain-Thani). To include antimetabolites azathioprine and methotrexate. Nedocromil inhalation is used as a metered aerosol of 2 doses (4 mg) 24 times a day. Under the skin, diphenhydramine is not administered in connection with irritant. Cromoglicic acid (cromolyn, Inta) prescribe inhaled in the form here or powder for inhalation 4-6 times a day. Inhibit the production of antibodies. Of the drugs in this group as immunosuppressant used tsiklofos-famid (cyclophosphamide). For the prevention of graft rejection reactions drug is administered intra-tively, and then continue to be given by mouth. Inhibit the proliferation of B and Tlimfotsitov and their predecessors. As antitumor emigrated cyclophosphamide used in lung cancer, breast cancer, chlamydia, lymphocytic leukemia. Glucocorticoids are used mainly in severe and moderate forms of allergy (anaphylaxis, angioedema, serum sickness, etc.). 266) have anti-inflammatory and immunosupres-sive properties. Is also a sedative, antiemetic effect, potentiates the effect of narcosis, hypnotics and analgesic substances.
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